Pharmaceutical Raw Material Tacrolimus CAS 104987-11-3 for Immune Suppressant
|FOB Price:||US $2-5 / Bag|
|Min. Order:||1 Bag|
|Min. Order||FOB Price|
|1 Bag||US $2-5/ Bag|
|Payment Terms:||L/C, T/T, D/P, Western Union, Paypal, Money Gram, Bitcoin|
- Model NO.: 104987-11-3
- Customized: Customized
- Suitable for: Adult, Bodybuilders
- Purity: >99%
- Mf: C44h69no12
- Payment Terms: Western Union, Bitcoin, Bank Transfer, T/T, Money
- Delivery Time: Within 8 Hours After Receiving Ypur Payment
- Quality: Wondful
- Transport Package: Disguised and Discreet
- Origin: Guangzhou
- Powder: Yes
- Certification: GMP, HSE, ISO 9001, USP, BP, Ukas
- State: Solid
- CAS: 104987-11-3
- MW: 804.02
- Shipment Way: DHL, TNT, UPS, EMS, Hongkong Post
- Storage: Keep in Cool and Dry Place, Away From Light
- Trademark: kafen
- Specification: USP, BP, GMP, ISO9001
- HS Code: 3002200000
Melting Point: 113-115° C
Boiling Point: 871.7 ° C at 760 mmHg
Appearance: White powder
Storage: Store in a cool, dry place. Do not store in direct sunlight. Store in a tightly closed container.
|Identification (IR)||Should match with working standard||Confirms|
|Water by KF||Not more than 0.5%||0.14%|
|Loss on drying||Not more than 0.5%||0.17%|
|Residue on ignition||Not more than 0.2%||0.05%|
|Heavy Metals||Not more than 20ppm||Confirms|
|Single maximum impurity||Not more than 0.5%||0.34%|
|Total impurities||Not more than 1.0%||0.66%|
|Assay by HPLC||98.0% -102.0%||101.0%|
|Conclusion||conforms with USP 32 Standard|
"Tacrolimus" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro.
Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis after bone marrow transplants, and the skin condition vitiligo.
Tacrolimus is chemically known as a macrolide. It reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506 binding protein) creating a new complex. This FKBP12-FK506 complex interacts with and inhibits calcineurin thus inhibiting both T-lymphocyte signal transduction and IL-2 transcription.
Tacrolimus is used together with other medicines to prevent the body from rejecting a transplanted organ (eg, kidney, liver, or heart). This medicine may be used with steroids, azathioprine, basiliximab, or mycophenolate mofetil. Tacrolimus belongs to a group of medicines known as immunosuppressive agents.
Tacrolimus is a very strong medicine. It can cause side effects that can be very serious, such as kidney problems. It may also decrease the body's ability to fight infections. You and your doctor should talk about the benefits of this medicine as well as the risks of using it.
Tacroz Forte Ointment (Tacrolimus) is used to treat atopic dermatitis (more commonly known as eczema). It is a topical medication which is normally prescribed for patients who have not responded successfully to other eczema medication.
The ointment is a type of topical calcineurin inhibitor (TCIs) that works by weakening the patient`s immune system, which as a consequence directly reduces the severity of eczema and its symptoms. It should not be used by patients who have any kind of weak immune system.
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|Pentadecapeptide BPC 157||2mg|
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