75921-69-6 Growth Hormone Peptides Raw Powder Mt1 Melanotan 1 99%
|FOB Price:||US $0.5-5 / g|
|Min. Order:||10 g|
|Min. Order||FOB Price|
|10 g||US $0.5-5/ g|
|Transport Package:||According to Your Requirements|
|Payment Terms:||L/C, T/T, D/P, Western Union, Paypal, Money Gram, Bitcoin|
- Model NO.: 75921-69-6
- Customized: Customized
- Suitable for: Elderly, Adult, Body Builder
- Purity: >99%
- Shelf Life: Two Years
- Storage: Keep in Cool and Dry Place, Away From Light
- Delivery Time: Within 12 Hours After Receiving Ypur Payment
- CAS: 75921-69-6
- MW: 1646.845
- Specification: Qualified
- HS Code: 3001909099
- Powder: Yes
- Certification: GMP, HSE, ISO 9001, USP, BP, Ukas
- State: Solid
- Appearance: White Lyophilized Powder
- After Sale Service: Excellent
- Shipment Way: EMS, HK Post, DHL, TNT, UPS, FedEx, Aramex
- Quality: Wondful
- Mf: C78h111n21o19
- Trademark: kafenbio
- Origin: China
75921-69-6 Growth Hormone Peptides Raw Powder MT1 Melanotan 1 99%
Alias: Melanotan-1, Melanotan I
Appearance: White Lyophilized Powder
Storage: Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18° C. Upon reconstitution of the peptide it should be stored at 4° C between 2-21 days and for future use below -18° C.
Melanotan 1 (also referred to as Afamelanotide) is a synthetic peptide variant of a peptide hormone, called alpha-Melanocyte stimulating hormone or MSH that is naturally produced in the body and is responsible for stimulating melanogenesis, a peptide process for pigmentation of the skin. Alpha-MSH activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido via these melanocortin receptors. As a result, Melanotan-1 sunless skin tanning effects. While Melanotan 2 and PT-141 have been studied at length as a potential remedies for the treatment of sexual dysfunction, Melanotan-1 has been researched extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis-stimulating properties.
Both Melanotan-1 and Melanotan 2 are analogs of the peptide hormone alpha-melanocyte stimulating hormone (α -MSH) that tend to induce skin tanning. Unlike Melanotan 1, Melanotan 2 has been shown to have aphrodisiac properties, the additional effect of increasing libido. Melanotan-1 is a non selective agonist of the melanocortin receptors (MC1R, MC3-5R). As an analogue of α -MSH, its mechanism of action is biomimicry of the natural mammalian tanning process.
3.Description and use :
Melanotan-1(MT-1) sometimes referred to as Afamelanotide, is a synthetic alpha-melanocyte stimulating hormone (a-MSH) peptide analog first developed at the University of Arizona and later by Clinuvel..
It acts on the melanocortin system and induces melanogenesis in human and animal trials.MT-1 can induce tanning in human volunteers who are known to tan easily in response to sunlight. Latest studies suggests that MT-1 has a highly effective for treatment of erythropoetic protoporphyria.
In the US about two-thirds of patients suffered erythropoetic protoporphyriaare receiving MT-1 as treatment, most of them claim that their symptomatic relief met expectations.
first ,i have to say that's very important to expose all parts of the body to equal amounts of sunlight or ultraviolet radiation.
-->>.The loading phase :
Dosages is 0.5 to 2mg are injected subcutaneously daily. normally about 7 to 10 days
--->>.The maintenance phase:
Usually the maintenance phase dose is 0.5mg taken twice per week .while,This might be different depending on person's reacts.
If the tan is getting lighter the dosage might be increased ,and short the period between injections.
however If getting to dark the dosage should be lowered or the injection frequency decreased.
Melanotan-1 Mechanism of Action :
Melanotan produces its photoprotective effects by triggering a 'signaling cascade' via its activation of the MC1R on melanin-producing cells known as melanocytes. Upon Melanotan binding with the MC1R on the surface of melanocytes in the epidermal layer of the skin, it begins a series of actions and reactions that result in melanocytes favoring the production of eumelanin .
5.Melanotan 1 and Melanotan 2:
Melanotan's peptide structure is almost the same as our endogenously produced melanocyte-stimulating hormone.
Melanotan 2 has a shorter sequence of amino acids slightly different than melanotan 1. MT2 can bind to the melanocortin-3 and 4 receptors and this binding will cause increases a side effect of sexual arousal.
Some people choose MT-1 because it causes tanning with less side effects then Melanotan 2. while ,on a mg for mg basis effectively you need less in terms of milligram weight of MT II to achieve tanning results compared to MT1.
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